thymidine相关论文
Background Taxol is a powerful chemotherapy agent that targets the microtubule cytoskeleton, leading to mitotic arrest a......
A MRI nanosensor for Hg (II) was developed based on superparamagnetic iron oxide nanoparticles (SPIO NPs).The detection ......
<正> The Chinese hamster cell line Wg3-h and human lymphocytes were used as parental cells for the fusion experiment. Th......
To explore correlation between the tk gene structure of pseudorabies virus (PRV) and its virulence, to study the effect ......
Antisense oligonucleotide to insulin-like growth factorⅡ induces apoptosis in human ovarian cancer A
The effects of antisense oligonucleotide to insulin-like growth factor 11 (IGFII) to induce apoptosis in human ovarian c......
Isoflavone genistein protects high glucose-induced human aortic endothelial cell apoptosis through e
Objective The aim of this study was to determine if isoflavone genistien has protective effects against high glucose-ind......
Kaposi’s sarcoma-associated herpesvirus (KSHV) was first identified as the etiologic agent of Kaposi’s sarcoma (KS) in......
The selenium derivatization of nucleic acids and nucleic acid-protein complexes has provided a powerful tool to solve ph......
THE LOCALIZATION OF ADRENOMEDULLIN IN RAT KIDNEY TISSUE AND ITS INHIBITORY EFFECT ON THE GROWTH OF C
Adrenomedullin（AM），anovelhypotensivepeptideoriginallyisolatedfromhumanpheochromocytoma（１），wassynthesizedinvarioustissues（２，３）．Thecalc......
Expression of thymidine kinase mediated by a novel non-viral delivery system under the control of va
AIM: To investigate the killing efficiency of a recombinant plasmid containing a thymidine kinase (TK) domain insert dri......
This work is to demonstrate feasibility of imaging the expression of herpes simplex virus 1-thymidine kinase (HSV1-tk) r......
AIM To investigate the effects of taxol onSMMC-7721 human hepatoma and itsmechanisms.METHODS In vitro cell growth was a......
Coexpression of vascular endothelial growth factor and its receptor KDR on gastric adenocarcinoma MG
Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF), is an angiogenic factor pl......
Effects of herpes simplex virus thymidine kinase/acyclovir system on growth of human pulmonary adeno
Objective: To observe the effect of anciclovir (ACV) treatment on tumors induced by inoculation of TK gene-transfected ......
The promoting molecular mechanism of alphafetoprotein on the growth of human hepatoma Bel7402 cell l
AIM:The goal of this study was to characterize the AFPreceptor,its possible signal transduction pathway and itsprolifer......
AIM:Somatostatin and its analogues may suppress thegrowth of various tumor cells.However,the effect ofoctreotide on gro......
Correlation of thymidylate synthase,thymidine phosphorylase and dihydropyrimidine dehydrogenase with
AIM:To determine the expression levels of three metabolicenzymes of fluoropyrimidines:thymidylate synthase (TS),thymidi......
AIM:To study the effect of red oil A5 on pancreatic cancercells and its possible mechanisms.METHODS:Effect of different......
AIM:To detect the thymidine phosphorylase(dThdPase)expression in human colorectal cancer tissues and cells.METHODS:Fort......
Construction and identification of recombinant vectors carrying herpes simplex virus thymidine kinas
AIM:To construct and identify the recombinant vectorscarrying herpes simplex virus thymidine kinase (HSV-TK) andtumor n......
Do there exist synergistic antitumor effects by coexpression of herpes simplex virus thymidine kinas
AIM:To evaluate the synergistic antitumor effects of herpessimplex virus thymidine kinase (HSV-TK) together with tumorn......
Herpes simplex vires thymidine kinase and ganciclovir suicide gene therapy for human pancreatic canc
AIM:To investigate the in vitro effects of suicide genetherapy system of herpes simplex virus thymidine kinasegene (HSV......
为了研究急性髓细胞白血病 (AML)细胞诱导成树突状细胞 (DC)的方法及其DC的功能 ,分离 2 5例AML患者骨髓或外周血单个核细胞 ,在含......
目的 研究转化生长因子(TGF)-β1对横纹肌肉瘤RD细胞系的生长调节及作用机制.方法 3H-thymidine 掺入实验、四甲基偶氮唑盐(MTT)实......
Aim:To assess the inhibitory effect of agmatine on tumor growth in vivo andtumor cell proliferation in vitro.Methods:Th......
Effect of p15~(INK4b) expression on the cell cycle and G_1 phase related regulatory genes in human m
Using the transfection technique, P151NK4b’ was introduced into P151NK4b gene deleted humanmelanoma A375 cells, and a ......
INHIBITION OF NASOPHARYNGEAL CARCINOMA AND EBV EARLY ANTIGEN INDUCTION BY CHINESE HERBS AND MARINE O
In this study,we have discovered two antineoplastic drugs,CH861 from Chinese medicinal herbs and MO871 from the marine ......
Activation of Signal Transducer and Activator of Transcription 5 (STAT5) in Splenocyte Proliferation
To investigate the role of signal transducer and transcriptional activator 5(STAT5)activated in ovalbumin(OVA)-induced ......
Effects of pinacidil on proliferation of cultured rabbit airway smooth muscle cells induced by endot
It has been found that the potassium channel dysfunction of the membrane of airway smooth muscle cells (ASMCs) is closel......
This study aimed at the effect of γ-emitting radionuclide l03Pd on the proliferation and apoptosis of vascular SMCs (s......
AIM:To investigate the expression between γ-aminobutyricacid (GABA) and glutamate decarboxylase and its relationwith d......
Lethiferous effects of a recombinant vector carrying thymidine kinase suicide gene on 2.2.15 cells v
AIM:To determine the lethiferous effects of a recombinantvector carrying thymidine kinase(TK)suicide gene on 2.2.15cell......
Kinase domain insert containing receptor promotor controlled suicide gene system kills human umbilic
AIM: To evaluate the killing effect of double suicide gene mediated by adenovirus and regulated under kinase domain inse......
Macrophage migration inhibitory factor stimulated by He/icobacter py/oriincreases proliferation of g
AIM: Helicobacter pylori (H pylori) is associated with increased gastric inflammatory and epithelial expression of macro......
There is increasing recognition of the potential morbidity and mortality associated with HIV-1 and hepatitis C (HCV) co-......
Objective Our aim was to investigate the frequency, phenotype and function of CD4+ CD25high regulatory T cells (Treg) in......
AIM: To investigate the effect of stable c-Fos overexpression on immortalized human hepatocyte (IHH) proliferation. METH......
ELECTRON MICROSCOPIC AUTORADIOGRAPHIC STUDIES ON DYNAMICS AND LOCATION OF DNA SYNTHESIS OF DUCK PLAG
Electron microscopic autoradiographic studies on the dynamics and location of DNAsynthesis by means of incorporation of......
Effect of Endothelin, Angiotensin Ⅱ and ANP on Proliferation of Vascular Smooth Muscle Cells and Car
By means of cell culture, ~3H-thymidine (~2H-TdR) incorporation and c-fos oncogene dot plotting technique, it was found......
Cell transformation as aberrant differentiation: Environmentally dependent Spontaneous transformatio
NIH 3T3 cells, a mouse fibroblast cell line used as routine target cells for transfection experiments, undergo spontaneo......
The inhibitory effect of rabbit blastocystic peptides (RBPs) on lymphocyte transfor-mation was studied by the method of......
实验用的大鼠为250～300克重的Wistar雄家鼠。一共做了41个移植,受肾者的两肾切除或不切除。14只对照将肾钳夹,时间与移植缺血期相......
眼科范围内抗病毒药物除对单纯疱疹治疗用药外,关于腺病毒等引起的眼病治疗药物几乎没有。现将角膜疱疹抗病毒药物的作用机制、用......
EFFECTS OF PARATHYROID HORMONE AND ESTRADIOL ON PROLIFERATION AND FUNCTION OF HUMAN OSTEOBLASTS FROM
The effect of parathyroid hormone (PTH) (0.01 nM-10 nM) and 17 -estradiol (E2, 1 nmol-10 nM) alone or in combination on ......
EFFECTS OF HYPOXIC ENDOTHELIAL CELL CONDITIONED MEDIUM ON PROLIFERATION AND COLLAGEN SYNTHESIS OF SM
The effects of hypoxic endothelial cell conditioned medium (HECCM) on proliferation and collagen synthesis of cultured p......
Thichosanthin(Tk), a polypeptide with 249 amino acid residues isolated and purified from a Chinese medicinal herb, showe......
High efficient generation of replication-defective adenoviruses containing thymidine kinase by homog
Background Suicide gene therapy is a widely used molecular treatment for head and neck cancer.In this study,we tryto us......
Thymidylate synthase and thymidine phosphorylase gene expression as predictive parameters for the ef
AIM: To investigate the prognostic role of thymidylate synthase (TS) and thymidine phosphorylase (TP) mRNA levels in T3 ......
The synthesis Of DNA, RNA and protein in L121O cells was inhibited by HHO7A in a dose-dependentand time-dependent way. H......
A monoclonal antibody, McAb-ST, specific for sterigmatocystin (ST) was produced in vitro and in vivo by a hybridoma anti......
